Diagnostic capacity and preliminary evaluation of Clock drawing Test, to order criteria from Cacho's version, for patients with mild Alzheimer's disease in Chilean population [Capacidad diagnóstica y validación preliminar del test del reloj, versión de cacho a la orden, para enfermedad de Alzheimer de grado leve en población chilena]

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dc.contributor.authorLópez, Norman
dc.contributor.authorAllegri, Ricardo
dc.contributor.authorSoto Añari, Marcio Fernando
dc.date.accessioned2019-01-29T22:19:54Z
dc.date.available2019-01-29T22:19:54Z
dc.date.issued2014
dc.description.abstractBackground: To perform a study with discriminant power and validity using the Clock drawing Test by instruction (CDTI) in patients with mild Alzheimer's disease (MAD). Materials and Methods: Phase I diagnostic test study. We included a healthy control arm of 58 elderly people and 40 cases with mild Alzheimer's disease. All participants were examined and diagnosed by clinical consensus. The MMSE, CDTI and clinical record were obtained. Results: There were significant differences between the study groups regarding cognitive tests' performance when comparing age and education, but no differences were found when comparing gender. ANCOVA test showed no significant effect exerted by the demographic variables on cognitive performance in any group. The sensitivity (CTO=84[%] vs MMSE=79, 3[%]), specificity (92, 5[%] vs 82, 5[%]) and diagnostic utility of the CDTO were higher than one's resulting form the MMSE (=0, 90, p=0, 000). The combined use of both instruments increased diagnostic capacity. The best cutoff point for the diagnosis of mild dementia was ≤ 6 points in CDTO and ≤ 23 in MMSE. Both instruments correlated statistically. Conclusions: The CTO is a useful test and can discriminate between cognitively healthy subjects and patients with EAL when appliying the "to order" criteria from Cacho's version.es_PE
dc.description.uriTrabajo de investigaciónes_PE
dc.identifier.issn10198113es_PE
dc.identifier.urihttps://hdl.handle.net/20.500.12590/15865
dc.language.isoenges_PE
dc.publisherFundacion para la difusion neurologica en Ecuador - FUNDINEes_PE
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84976385754&partnerID=40&md5=53fa6cf5c7e2c50e1d7474ff3d5f9da3es_PE
dc.rightsinfo:eu-repo/semantics/restrictedAccesses_PE
dc.sourceRepositorio Institucional - UCSPes_PE
dc.sourceUniversidad Católica San Pabloes_PE
dc.sourceScopuses_PE
dc.subjectagees_PE
dc.subjectagedes_PE
dc.subjectAlzheimer diseasees_PE
dc.subjectArticlees_PE
dc.subjectChileanes_PE
dc.subjectclinical articlees_PE
dc.subjectclock drawing testes_PE
dc.subjectcognitiones_PE
dc.subjectcontrolled clinical triales_PE
dc.subjectcontrolled studyes_PE
dc.subjectdiagnostic test accuracy studyes_PE
dc.subjectdiagnostic valuees_PE
dc.subjectdiscriminant validityes_PE
dc.subjectdisease severityes_PE
dc.subjecteducational statuses_PE
dc.subjectfemalees_PE
dc.subjecthumanes_PE
dc.subjectmalees_PE
dc.subjectMini Mental State Examinationes_PE
dc.subjectsensitivity and specificityes_PE
dc.subject.ocdehttps://purl.org/pe-repo/ocde/ford#5.01.02es_PE
dc.titleDiagnostic capacity and preliminary evaluation of Clock drawing Test, to order criteria from Cacho's version, for patients with mild Alzheimer's disease in Chilean population [Capacidad diagnóstica y validación preliminar del test del reloj, versión de cacho a la orden, para enfermedad de Alzheimer de grado leve en población chilena]es_PE
dc.typeinfo:eu-repo/semantics/article
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